- Industry: Library & information science
- Number of terms: 152252
- Number of blossaries: 0
- Company Profile:
The National Library of Medicine (NLM), on the campus of the National Institutes of Health in Bethesda, Maryland, is the world's largest medical library. The Library collects materials and provides information and research services in all areas of biomedicine and health care.
Gene which serves to protect cells from entering a cancerous state.
Note: According to Knudson’s “two-hit” hypothesis, both alleles of a particular tumor suppressor gene must acquire a mutation before the cell will enter a transformed state.
Industry:Biology; Chemistry
General description of all of the signs and symptoms of exposure to a toxicant.
Note: Signs are the overt (observable) responses associated with exposure (such as convulsions, death, etc.) whereas symptoms are covert (subjective) responses (such as nausea, headache, etc.).
Industry:Biology; Chemistry
Generation and manipulation of stem cells with the objective of deriving cells of a particular organ or tissue to treat a disease.
Industry:Biology; Chemistry
Genetic method for analysing the interactions of proteins.
Note: Frequently restricted to man-made compounds.
Industry:Biology; Chemistry
Global analysis of gene expression to identify and evaluate changes in synthesis of mRNA after chemical exposure.
Industry:Biology; Chemistry
Global analysis of gene expression using a variety of techniques to identify and characterize proteins.
Note: It can be used to study changes caused by exposure to chemicals and to determine if changes in mRNA expression correlate with changes in protein expression: the analysis may also show changes in post-translational modification, which cannot be distinguished by mRNA analysis alone.
Industry:Biology; Chemistry
Global term for the whole process from hazard identification to risk management.
Industry:Biology; Chemistry
Group of all reference individuals used to establish criteria against which a population that is being studied can be compared.
Industry:Biology; Chemistry
Hardening of an organ or tissue, especially that due to excessive growth of fibrous tissue.
Industry:Biology; Chemistry
