Home > Terms > English, UK (UE) > pethidine
pethidine
Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. It was later discovered that these were all myths and that it carried an at least equal risk of addiction, possessed no advantageous effects on biliary spasm or renal colic compared to other opioids and that, due to its toxic metabolite, norpethidine, it was more toxic than other opioids, especially during long-term use.
- Part of Speech: noun
- Synonym(s):
- Blossary: Illegal Drugs
- Industry/Domain: Law enforcement
- Category: Drug trafficking
- Company:
- Product:
- Acronym-Abbreviation:
Other Languages:
Member comments
Terms in the News
Featured Terms
technical rescue
Technical rescue refers to special tasks of saving life or property that employ tools and skills going beyond those normally practiced for fire ...
Contributor
Featured blossaries
Marouane937
0
Terms
58
Blossaries
3
Followers
10 Of The Most Dangerous Hit-men of All Time
Browers Terms By Category
- Algorithms & data structures(1125)
- Cryptography(11)
Computer science(1136) Terms
- Wedding gowns(129)
- Wedding cake(34)
- Grooms(34)
- Wedding florals(25)
- Royal wedding(21)
- Honeymoons(5)
Weddings(254) Terms
- General accounting(956)
- Auditing(714)
- Tax(314)
- Payroll(302)
- Property(1)
Accounting(2287) Terms
- Air conditioners(327)
- Water heaters(114)
- Washing machines & dryers(69)
- Vacuum cleaners(64)
- Coffee makers(41)
- Cooking appliances(5)
Household appliances(624) Terms
- Misc restaurant(209)
- Culinary(115)
- Fine dining(63)
- Diners(23)
- Coffehouses(19)
- Cafeterias(12)